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TNF-RELATED APOPTOSIS-INDUCING LIGAND
Descriptors Found:
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DeCS
Descriptor
English
:
TNF-Related Apoptosis-Inducing Ligand
Descriptor
Spanish
:
Ligando Inductor de Apoptosis Relacionado con TNF
Descriptor
Portuguese
:
Ligante Indutor de Apoptose Relacionado a TNF
Synonyms
English
:
Tumor Necrosis Factor Ligand Superfamily Member 10
Tree Number:
D12.644.276.374.750.625
D12.776.467.374.750.625
D23.529.374.750.625
Definition
English
:
A transmembrane-protein belonging to the TNF
family
of intercellular signaling
proteins
. It is a widely expressed ligand that activates
APOPTOSIS
by binding to
TNF-RELATED APOPTOSIS-INDUCING LIGAND
RECEPTORS. The membrane-bound form of the protein can be cleaved by specific
CYSTEINE ENDOPEPTIDASES
to form a soluble ligand form.
History Note
English
:
2007(2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52298
Unique Identifier:
D053221
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS